Multi-part problem with mail."warning: connect to transport amavis:... and [UPDATE] It seems that amavis is not my only problem. Although I can connect to the mail server to receive mail, any attempts to send mail to the account, from another email address or relay email from the account, to another email address fail. Maillog has this to say: ("SOURCE.USER@SOURCE-USER.com" = non-ipconfig source. "DESTINATION.USER@DESTINATION-USER.com" = ipconfig user destination, in this case "web5_USER". Code: Dec 15 05:34:54 sd-7405 postfix/smtpd: connect from unknown[XX.XXX.XXX.XX] Dec 15 05:34:55 sd-7405 postfix/smtpd: NOQUEUE: reject: RCPT from unknown[XX.XXX.XXX.XX]: 554 <SOURCE.USER@SOURCE-USER.com>: Relay access denied; from=<DESTINATION.USER@DESTINATION-USER.com> to=<SOURCE.USER@SOURCE-USER.com> proto=SMTP helo=<WORK> Dec 15 05:34:55 sd-7405 postfix/smtpd: disconnect from unknown[XX.XXX.XXX.XX] Dec 15 05:34:56 sd-7405 dovecot: pop3-login: Login: user=<web5_USER>, method=PLAIN, rip=::ffff:220.127.116.11, lip=::ffff:18.104.22.168 Dec 15 05:34:57 sd-7405 dovecot: POP3(web5_USER): Disconnected: Logged out top=0/0, retr=0/0, del=0/0, size=0 Maillog also has this in it: Code: Dec 15 05:38:15 sd-7405 postfix/anvil: statistics: max connection rate 1/60s for (smtp:22.214.171.124) at Dec 15 05:34:54 Dec 15 05:38:15 sd-7405 postfix/anvil: statistics: max connection count 1 for (smtp:126.96.36.199) at Dec 15 05:34:54 Dec 15 05:38:15 sd-7405 postfix/anvil: statistics: max cache size 1 at Dec 15 05:34:54 [/UPDATE] I'm now testing out my mail server and I get this in the "maillog" file whenever mail attempts be received or sent. By way of reference, I used the http://www.howtoforge.com/perfect_setup_fedora_core_5 , except on a 32 bit box, which works perfectly otherwise, and I already checked and "amavis" and clamd.amavisd are both running as the same user, namely "amavis". I can also telnet to 10024 with no problem. To be honest, I'm no longer sure that amavis was even part of the ISPConfig install or if it was instead installed as a failed attempt at getting postfix installed and working previously. One thing I do know though is that my postfix main.cf file is the same as it is shown in the Howto I listed, if that is any help. Since I don't actually have any sites live yet, I'm almost tempted to uninstall it all and start over with the same howto but I'm worried that I'd end up not uninstalling something that needed to be and be in worse shape. Any help, including a pointer to how to start over if that is the best route, would be greatly appreciated!