Tutorial PureFTP contains: You should already have set up a basic CentOS 6.4 system, for example as described in the first six chapters of this tutorial: The Perfect Server - CentOS 6.4 x86_64 (Apache2, Dovecot, ISPConfig 3). [...] cat /dev/null > /etc/pure-ftpd/pureftpd-mysql.conf But pureftpd-mysql.conf file has the data necessary for ISPConfig3, other than for PureFTP. Example for PureFTP: MYSQLDatabase pureftpdExample for ISPConfig: MYSQLDatabase dbispconfigand all other. How to get the functionality of the FTP server with virtual users without taking functionality webmasters ftp accounts ISPConfig? It is unfortunate that ISPConfig 3 can not add FTP users are limited to the dedicated sub-folder in a folder such as public-ftp folder for each domain. Ps. Sorry for the lack of knowledge of English.