I've installed ISPConfig onto FC4 after upgrading MySQL and mysql-devel to 4.1.16 using a yum update. I appreciate that 4.1 uses a different password hash and therefore phpmyadmin won't set passwords correctly. Obviously I can set them correctly from the mysql prompt and by looking at the users table I can see that this does indeed change the password hash. In another post, Till says: How do I remove the old mysql-devel - do I need to? How exactly do I run the ISPConfig update? I suspect that this is going to become an increasing problem!