Hi, I have latest ISPConfig 18.104.22.168 installed with PHP Version 5.3.2-1ubuntu4.14. PHP is protected with the Suhosin Patch 0.9.9.1, and it is running as Fast-CGI on all websites. I have some problems understanding, how to properly configure PHP, PEAR and SMTP. First, I have SOME of 50 web sites running WITHOUT below problems, but the rest are having problems I describe below. I canot fugure out, where is the catch. 1.) ERROR when sending mail using PEAR: Failed opening required 'Mail.php' (include_path='.:/usr/share/php') in /var/www/clients/client1/web11/web/index.php The PHP script is exact copy of working script from another domain on the same server, but it does not work. PATH /usr/share/php is correct, permissions are 644 on all files. Any idea? 2.) SMTP proxy I have a special SMTP Antispam and antivirus proxy server, setup only for my web servers to send mail through it. On my Windows servers I have PHP.INI configured: Code: [mail functions] SMTP = 22.214.171.124 smtp_port = 587 And it works fine. But not on this Linux server - from mail.info log, that server is trying to contact destination SMTP directly. I have edited PHP.INI in both locations: /etc/php5/cgi/php.ini /etc/php5/apache2/php.ini Weird is, that when I print phpinfo(), I see only user-specific PHP is loaded: Configuration File (php.ini) Path /etc/php5/cgi Loaded Configuration File /var/www/conf/web11/php.ini Any idea what I am doing wrong?