The reason was:
receive_override_options = no_address_mappings
after i disabled this line, everything works again like a chram....
First, my exmaple was wrong! sorry for it. Port 587 was used.
Nov 12 15:19:29 mail01 postfix/submission/smtpd: 7477631A72:...
mails are ususally send through submission, Port 587
smtp inet n - y - - smtpd
i have a weird error with the current setup. The server was freshly setup one week ago with 3.1.15p2 on Debian Buster with rspamd config....
Separate names with a comma.