I have exactly the same problem as rdells. Since today, some large emails are returned and I get the "Mail Quota Exceed!" message.
I haven't updated anything in my server, but I have rebooted it (it was near 130 days without rebooting). I'm using OpenSuse 10, ISPConfig 2.1.1 and Postfix 2.2.5-5.
I have disabled the antivirus and now it seems to work, but I don't understand where's the problem...
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