ClamAV-clamd av-scanner FAILED in ISPConfig3.0.2.1 3

[pinguinito]

Mail Queue:

(host 127.0.0.1[127.0.0.1] said: 451 4.5.0 Error in processing, id=14003-02, virus_scan FAILED: virus_scan: ALL VIRUS SCANNERS FAILED: ClamAV-clamd av-scanner FAILED: run_av error: Too many retries to talk to /var/run/clamav/clamd.ctl (Can't connect to UNIX socket /var/run/clamav/clamd.ctl: No such file or directory) at (eval 88) line 309.; ClamAV-clamscan av-scanner FAILED: run_av error: run_av: Exceeded allowed time at (eval 88) line 516. (in reply to end of DATA command))

And this is the Mail Error-log:

May 15 17:40:43 server1 amavis[14904]: (14904-02-4) (!!)ClamAV-clamd av-scanner FAILED: run_av error: Too many retries to talk to /var/run/clamav/clamd.ctl (Can't connect to UNIX socket /var/run/clamav/clamd.ctl: No such file or directory) at (eval 88) line 309.
May 15 17:40:43 server1 amavis[14904]: (14904-02-4) (!!)WARN: all primary virus scanners failed, considering backups

And I don't have this directory:
/var/run/clamav/clamd.ctl

I assume that creating this directory I will fix my problem but, how?

thanks to all of you in this community