In the /etc/apache2/vhosts/Vhosts_ispconfig.conf there are 2 lines per domain by default that conflict with common dircectories used by CMS Software.
AliasMatch ^/~([^/]+)(/(.*))? /var/www/web3/user/$1/web/$3
AliasMatch ^/users/([^/]+)(/(.*))? /var/www/web3/user/$1/web/$3
So when I go to http://dannyweaver.com/users/login.php
I get a 404. I use Genu for my personal site. While its easy enough for me to comment the second line listed above, most users cannot do this. I don't think Genu is the only CMS that uses the users directory in its structure and it would be better if ISPConfig used a less common name. I'm sure "ispusers" would work fine for 99.9% of people.
Also, I've been unable to figure out why these aliased dirs are there in the first place.
Lastly, you guys do a great job on ISPConfig, and I just sent off my email to join the Development Crew to help with Translation as I speak English, French, German and Esperanto. I'd love to do an Esperanto translation :-) Unfotunatly none of my secondary languages are strong, but the English translation of ISPConfig seems to be weak and that is where I wish the lend a hand the most as it is my native language.