1) You can mix different Linux distributions in a multiserver setup. As multiserver guides are available for debian only at the moment, please use the apropriate chapters of the perfect setup guides indstead. E.g. if you want to install a mail server, use the mail chapters + install mysql and php-cli plus the php modules. >ou can also just follow the while perfect setup and just install ispconfig at the end in expert instead of standard mode to join a master server. On the master itself, all you have to do is to add a new mysql root user for the new slave before you install ispconfig.