Originally Posted by breakaway
However, I have found that even after saving the above directive into ISPConfig for that site and reloading (and also restarting) nginx, phpMyAdmin is accessible via http on port 8081!
This is the apps vhost that comes with ISPConfig. you can find it in /etc/nginx/sites-available/apps.vhost. If you like to disable phpMyAdmin there, please don't forget to disable it in the apps vhost template in /usr/local/ispconfig/server/conf as well.