Solved the part with apache not starting.
Didn't think that the domain with ssl that was working could be a problem. After I removed these apache could start.
But now my problem is that the vhost file doesn't get the SSL part added again. I have tried "Delete certificate" and remove the tick mark from SSL inside ISPConfig panel. Added the SSL tick mark again and "Create certificate" but when I check the vhost SSL part is not added.
I have checked on ther server and cert files are created in the ssl folder for the domain.