The problem seem to exist since quite some time as 1657 changes are not processed yet, or did you choose resync one or more times? A reason for your problem can be changed php.ini settings which can cause the server process to hang, e.g. when you disabled some functions in php.ini which are required by ispconfig. Did you do any configuration changes, updates or did you install any php modules (especially apc can cause problems) before the problems started?
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