Still 500 error after restart apache.
Checked the open-basedir setting in ISPConfig but that looks ok too:
Tried with the ip adress again. But also the 500 server error.
What i did next was I put a index.html in the /usr/share/phpmyadmin folder with some dummy text in it.
When I go to the url http://myip/phpmyadmin/index.html
the page with dummy text is shown.
Alias works, but the index.php gives the error I think. How can I check what is going wrong?