yes its working tanx
so my conclusion is that ISPconfig add those 3 lines and they are necsesary but the line
relay_domains = $#mydestination
has that # that damages everything. sooo the solution is to erase that # (sharp)
relay_domains = $mydestination
that is a bug that can keep you 1 complete day or even more stopped at work so plezz developrers fix it.
tanx everyone im starting to enjoy my ISPconfig