It seems your vsftpd was run by xinetd, so you should have restarted xinetd.
But now that you want to run it with an init script, you should check if /etc/init.d/vsftpd uses the correct config file (I guess it looks for /etc/vsftpd.conf instead of /etc/vsftpd/vsftpd.conf).
You can kill the running vsftpd process with