Thank you very much for the reply...
I did look into 'Vhosts_ispconfig.conf' and all appeared to be fine.
No Unix updates or the like were installed/updated.
This machine at random completely takes down all Internet connectivity for ALL devices connected forcing me to disconnect it's Ethernet cable to remove it from the network all together.
Most often I have to go through a series of stopping and starting 'shorewall' in addition to running 'iptables -F' and in a lot of cases I must reboot the server all together before being able to reintroduce it to the network?...
Strangely enough the box just began to serve the domains when requested last night out of the blue.
Have a great day