The ISPC installation runs on a dedicated server for one single customer only. I haven't had to access it in quite a while. The box uses Debian Edge 64 Bit and is up-to-date. It may be, that in the meantime after ISPC 2.2.22 there has been a MySQL update but I can't tell for sure.
Other than via apt-get update/upgrade there haven't been any changes to the databases. Currently there is 5.0.32-Debian_7etch5-log running with utf-8. PHPMyAdmin shows the database 'ispconfig' is utf8_general_ci.